| Event | Name(s) / School | Mark | Year |
| 50 Freestyle | Mosniak (Baldwin Wallace) | 20.94 | 2006 |
| 100 Freestyle | Mosniak (Baldwin Wallace) | 47.20 | 2006 |
| 200 Freestyle | Dorsch (John Carroll) | 1:44.28 | 2004 |
| 500 Freestyle | Schultz (Ohio Northern) | 4:46.23 | 2010 |
| 1000 Freestyle | Schmidt (Case Western Reserve) | 9:57.71 | 2019 |
| 1650 Freestyle | Forster (Baldwin Wallace) | 17:19.47 | 1994 |
| 100 Butterfly | McDonnell (John Carroll) | 51.37 | 2021 |
| 200 Butterfly | Boogart (Malone) | 1:59.46 | 2017 |
| 100 Backstroke | Roberts (Baldwin Wallace) | 54.38 | 2004 |
| 200 Backstroke | Gluck (Wooster) | 1:58.52 | 2020 |
| 100 Breaststroke | Turi (John Carroll) | 1:00.07 | 1992 |
| 200 Breaststroke | Frankle (Ohio Northern) | 2:12.87 | 2006 |
| 200 Individual Medley |
Lewis (Baldwin Wallace) |
1:59.50 | 2018 |
| 400 Individual Medley | Mudry (John Carroll) | 4:16.50 | 2021 |
| 200 Medley Relay | Morsch, Lewis, Shaw, Butt | 1:39.36 | 2019 |
| 400 Medley Relay | Campbell, Venos, McDonnell, Heller (John Carroll) | 3:31.09 | 2021 |
| 200 Freestyle Relay | Bayuk, Chalot, Parker, Bennett (Wooster) | 1:28.98 | 1998 |
| 400 Freestyle Relay | Sonnenberg, Mosniak, Grilli, Fournier (Baldwin Wallace) | 3:16.56 | 2006 |
| 800 Freestyle Relay | Koenen, Mellett, Kingsley, Olsavsky (Baldwin Wallace) | 7:31.75 | 2021 |
| 1-Meter Voluntary Dive | Richert (Baldwin Wallace) | 209.18 | 2011 |
| 1-Meter Optional Dive | Richert (Baldwin Wallace) | 343.43 | 2011 |
| 1-Meter Championship Dive | Richert (Baldwin Wallace) | 521.10 | 2009 |